Astronaut Mark Vande Hei works on the Cardinal Muscle investigation
Fireworks in Space: NASA’s Twins Study Explores Gene Expression and Cardinal Muscle investigation BioCells wells.
NASA astronaut and Expedition 65 Flight Engineer Mark Vande Hei performs microscopy operations to capture images of the Cardinal Muscle investigation BioCells wells aboard the International Space Station. This study tests whether such engineered tissues cultured in space could provide a model for studying muscle loss and assessing possible therapeutics prior to clinical trials.
Twenty Years and Counting
Thanks to the space station’s longevity, experiments can continue for months or even years. Scientists can design follow-up studies based on previous results, and every expedition offers the chance to expand the number of subjects for human research.
One area of long-term human research is on changes in vision, first observed when astronauts began spending months at a time in space. Scientists wondered whether fluids shifting from the lower to the upper body in microgravity caused increased pressure inside the head that changed eye shape. The Fluid Shifts investigation began in 2015 and continued to measure the extent of fluid shifts in multiple astronauts through 2020.1
Whether the original study is long or short, it can take years for research to go from the lab into practical applications. Many steps are involved, some of them lengthy. First, researchers must come up with a question and a possible answer, or hypothesis. For example, Fluid Shifts questioned what was causing vision changes and a possible answer was increased fluid pressure in the head. Scientists must then design an experiment to test the hypothesis, determining what data to collect and how to do so.
Thanks to the space station’s longevity, experiments can continue for months or even years. Scientists can design follow-up studies based on previous results, and every expedition offers the chance to expand the number of subjects for human research.